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Ethyl palmitoleate is a more lipophilic form of the free acid. It is one of the fatty acid ethyl esters that increase cytosolic Ca2+ concentration leading to pancreatic acinar cell injury due to excessive consumption of ethanol. Ethyl palmitoleate (10-100 µM) in addition to 850 mM ethanol resulted in sustained, concentration-dependent increases in Ca2+ that caused cell death.{14121} This fatty acid ethyl ester is also a potential biomarker for fetal exposure to alcohol.{14123}
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A medium-chain fatty acid; has been found at high levels in coconut oil; induces the activation of NF-κB and the expression of COX-2, iNOS, and IL-1α in RAW 264.7 cells at 25 µM
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A long-chain ω-3 fatty acid ethyl ester; dietary administration increases the ex vivo activity of hepatic β-oxidation enzymes at 41.4 g/100 g of total dietary fatty acids; reduces total hepatic triglyceride levels and increases the ω-3 fatty acid content of hepatic triglycerides and phospholipids, as well as increases the total levels of ω-3 fatty acids in rats; reverses increases in plasma cholesterol levels and reduces circulating triglyceride levels in rats fed a high-fat diet at 1 g/kg
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C22-Ceramide (N-Behenoyl-D-erythro-sphingosine) is an endogenous bioactive sphingolipid used in research on membrane dynamics and mitochondrial ceramide channel formation. It reduces the propensity of C16-ceramide channel formation in isolated rat liver mitochondria and in liposomes. Supplied as a solid white to off-white powder with high purity for analytical and biological studies.
Endogenous bioactive sphingolipid relevant to membrane and apoptosis studies.
Reduces propensity of C16-ceramide channel formation in mitochondria and liposomes.
White to off-white solid suitable for handling and formulation.
Purity 98.0% for reproducible experimental results.
Molecular formula C40H79NO3; molecular weight 622.06 g/mol.
Soluble in ethanol and DMF using ultrasonic and warming up to 60°C as needed.
Store at 4°C protected from light; in solution keep at -80°C (up to 6 months) or -20°C (up to 1 month).
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Estradiol (17 -estradiol -Estradiol E2 17 -Oestradiol) is a human sex hormone and steroid and the primary female sex hormone Estradiol upregulates IL-6 expression through the estrogen receptor (ER ) pathway
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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Pipecolic acid (Standard) is the analytical standard of Pipecolic acid This product is intended for research and analytical applications Pipecolic acid is a metabolite of lysine and an important precursor for many useful microbial secondary metabolites Pipecolic acid slows ferroptosis in diabetic retinopathy by inhibiting the YAP-GPX4 signaling pathway In addition Pipecolic acid can be used as a diagnostic marker for pyridoxine-dependent epilepsy[1][2][3]
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